Can AI Find the Cures We've Overlooked for Decades? - with Dr. David Fajgenbaum [FULL INTERVIEW]

AI and Healthcare • May 8, 2025
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AI and Healthcare is an engaging interview series featuring world-renowned leaders shaping the intersection of artificial intelligence and medicine. Discover how AI is transforming healthcare today, addressing real-world challenges and improving patient outcomes. Originally launched as the TARGET: Cancer Podcast in 2021, the series evolved after 75 episodes into a comprehensive platform for AI and healthcare conversations, building on 3M+ views under Dr. Juneja’s leadership. Stay up-to-date and inspired—subscribe today!

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The idea that artificial intelligence can uncover life-saving treatments hidden in plain sight is no longer science fiction. In a healthcare system that often favors costly innovation over accessible solutions, using AI to repurpose existing drugs offers a path to faster, affordable breakthroughs. For a summary and key takeaways, visit: https://xcures.com/ai-and-healthcare/episodes/can-ai-find-cures-overlooked-for-decades/ Join Dr. Sanjay Juneja and Dr. David Fajgenbaum (https://en.wikipedia.org/wiki/David_Fajgenbaum), co-founder of Every Cure, as they reveal how AI is accelerating the identification of overlooked therapies for rare and complex diseases. Learn about the critical frameworks behind drug repurposing, how predictive models like Matrix are reshaping disease treatment, and why open-source collaboration could transform healthcare delivery. If you are a physician, healthcare executive, engineer, or healthcare IT leader, this discussion offers essential insights into the future of clinical decision-making. - - - -TimeStamps - - - - 00:00 Introduction 02:00 The Concept of Drug Repurposing 04:38 AI's Role in Drug Repurposing 07:43 Personalized Medicine and AI 18:03 Open Source Drug Repurposing 25:57 Financial Realities in Healthcare 28:19 AI in Rare Disease Treatment 34:10 Challenges with Supplements and Herbals 40:27 Excitement and Concerns with AI in Medicine 49:06 How You Can Help Every Cure - - - - - - - - #aiinhealthcare #DrugRepurposing #EveryCure #precisionmedicine 📌Watch now to understand how data structuring transforms AI's role in healthcare and why it matters for your organization. — ABOUT DR. SANJAY JUNEJA — Dr. Sanjay Juneja, a hematologist and medical oncologist widely recognized as “TheOncDoc,” is a trailblazer in healthcare innovation and a rising authority on the transformative role of AI in medicine. Garnering over 750k followers and 20 million views on social media, Dr. Juneja’s unique ability to simplify complex topics has earned him global acclaim. His debut podcast, Target Cancer: Podcast, amassed over 3 million downloads in more than 100 countries within just two years, setting the stage for his current AI-focused series featuring world-renowned guests. He currently serves as the VP of Clinical AI Operations at Tempus AI. https://www.linkedin.com/in/sanjayjunejamd/ — ABOUT DAVID FAJGENBAUM — David Fajgenbaum, MD, MBA, MSc, is a physician-scientist at the University of Pennsylvania and one of the youngest professors to receive tenure in the history of Penn Medicine, co-Founder & President of the Castleman Disease Collaborative Network (CDCN), co-Founder & President of Every Cure, and national bestselling author of ‘Chasing My Cure: A Doctor’s Race to Turn Hope Into Action‘. He is also a patient battling a deadly disease which he discovered a repurposed treatment for that is saving his life and others. Through his work at the University of Pennsylvania’s Center for Cytokine Storm Treatment & Laboratory, CDCN, and Every Cure, he has identified and/or advanced 16 other treatments for diseases they weren’t initially intended for. https://en.wikipedia.org/wiki/David_Fajgenbaum Additional listening channels, at xcures.com/ai-and-healthcare Views expressed by Dr. Juneja, Mr Newton, and guests are solely their own and are not attributable to xCures, Tempus, or any of our guests' affiliations.

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