Logarithmic nature of the brain 💡

Video Description

Shortform link: https://shortform.com/artem My name is Artem, I'm a computational neuroscience student and researcher. In this video we will talk about the fundamental role of lognormal distribution in neuroscience. First, we will derive it through Central Limit Theorem, and then explore how it support brain operations on many scales - from cells to perception. Special thanks to Crimson Ghoul for providing English subtitles! REFERENCES: 1.Buzsáki, G. & Mizuseki, K. The log-dynamic brain: how skewed distributions affect network operations. Nat Rev Neurosci 15, 264–278 (2014). 2.Ikegaya, Y. et al. Interpyramid Spike Transmission Stabilizes the Sparseness of Recurrent Network Activity. Cerebral Cortex 23, 293–304 (2013). 3.Loewenstein, Y., Kuras, A. & Rumpel, S. Multiplicative Dynamics Underlie the Emergence of the Log-Normal Distribution of Spine Sizes in the Neocortex In Vivo. Journal of Neuroscience 31, 9481–9488 (2011). 4.Morales-Gregorio, A., van Meegen, A. & van Albada, S. J. Ubiquitous lognormal distribution of neuron densities across mammalian cerebral cortex. http://biorxiv.org/lookup/doi/10.1101/2022.03.17.480842 (2022) doi:10.1101/2022.03.17.480842. OUTLINE: 00:00 Introduction 01:15 What is Normal distribution 03:03 Central Limit Theorem 04:23 Normality in biology 05:46 Derivation of lognormal distribution 10:20 Division of labour in the brain 12:20 Generalizer and specialist neurons 13:37 How lognormality arises 15:19 Conclusion 16:00 Shortform: sponsor message 16:54 Outro CREDITS: Icons by https://biorender.com/ Mathematical animations were created using Manim CE python library - https://www.manim.community/