3 Supplements I STOPPED Taking for Lifespan Extension (They Don’t Make You Live Longer)

Video Description

💊 Not all “longevity supplements” actually extend lifespan — even if they sound great on paper. In this video, I break down 3 popular anti-aging supplements that I’m NOT taking for lifespan extension — and explain why the research doesn’t live up to the hype. These compounds often show promise in some cell and animal studies, but when it comes to the highest level of scientific evidence, they fail to deliver real increases in lifespan. As a medical doctor (MD) and certified strength and conditioning coach, I’ll walk you through: ✅ The mechanisms behind each compound and why they seemed promising ✅ The human and animal data that challenge their lifespan claims ✅ What they might still be good for — even if they don’t extend life 🚫 3 Supplements I’m NOT Taking for Lifespan Extension (2025 Update) 1️⃣ Resveratrol – Once thought to mimic calorie restriction and activate sirtuins for longevity, but lifespan benefits disappear in higher-order animal studies. 2️⃣ Fisetin – Marketed as a “senolytic” that clears aging cells, but large-scale Interventions Testing Program (ITP) data show no lifespan benefit in mice. 3️⃣ NMN / NR (NAD⁺ Precursors) – Boost NAD⁺ levels in blood, but no evidence yet that this translates into longer life in mammals. 📚 You’ll learn which of these supplements still have health benefits, and why they might belong in your stack for performance or health in general — but not necessarily for living longer. 🔥Timestamps 00:00 Why I STOPPED Taking These 3 Supplements for Lifespan Extension 00:39 Resveratrol -Inhibiting Hallmarks of Aging through Calorie Restriction Mimicking? 02:53 Resveratrol’s Positive Lifespan Extension Data 03:47 Resveratrol’s Negative Lifespan Extension Data 08:34 Fisetin - The Senolytic’s Mechanism for Decreasing Hallmarks of Aging 10:01 Fisetin’s Positive Lifespan Extension Data 10:54 Fisetin’s Negative Lifespan Extension Data 11:49 NAD+ Precursors - Increasing Sirtuin Activation to Slow Aging 13:31 Does NAD+ ACTUALLY Decrease with Age? 15:23 How to Best Raise NAD+ Levels - NMN vs NR? 16:59 NMN and NR’s Positive Lifespan Extension Data 18:14 NMN and NR’s Negative Lifespan Extension Data ▶️ Watch next: Top 5 Supplements to Actually Extend Lifespan https://www.youtube.com/watch?v=BwvSG5VpVaA 🔔 Subscribe for science-backed videos on longevity, functional medicine, and performance optimization. ⚕️ Medical Disclaimer: This video is for educational purposes only and does not constitute medical advice or a doctor-patient relationship. Always consult your licensed healthcare provider before starting any new supplement or treatment. #Longevity #Supplements #AntiAging #Resveratrol #Fisetin #NMN #NR #NAD #LifespanExtension #FunctionalMedicine #HealthOptimization