TRT: Who Actually Needs It? Risks, Benefits, and Fertility Considerations | Dr. Suks Minhas

Live Well Be Well with Sarah Ann Macklin October 24, 2025
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👉 Practical beats perfect. Here’s a free 5-recipe PDF I use to support energy and stress during busy weeks. https://sarahannmacklin.com/5_free_recipes 👉 If this resonates, you can join the thousands who read The Compassionate Cure each week. https://sarahmacklin.substack.com/ Watch the FULL podcast here: https://youtu.be/Lw6iZbZBiw8 Thinking about TRT for low testosterone? This clip takes a closer look at who genuinely benefits from testosterone replacement therapy, what current evidence suggests about safety, and why fertility planning is crucial. I’m exploring with my guest how to distinguish primary from secondary hypogonadism, why symptoms plus true biochemical low testosterone are needed for a diagnosis, and the point that if total testosterone is above 12, TRT isn’t indicated. This discussion focuses on updated data around prostate and cardiovascular risk, key contraindications such as active prostate cancer, polycythemia, and heart failure, and the reality that exogenous testosterone suppresses FSH and sperm production, acting like a male contraceptive and not always fully reversible. We also cover off-label options like clomiphene and hCG to support endogenous testosterone when fertility is a priority, the importance of screening for metabolic issues like dyslipidemia and prediabetes, lifestyle considerations, and the social pressures that drive recreational use. There’s a brief reflection on age-related declines, the idea that testosterone may drop after men have children, and how broader environmental factors might fit into the picture. As a nutritionist and health communicator, I aim to connect the science with practical, balanced advice so you can discuss options confidently with your clinician. *** This episode is sponsored by: NOWATCH: Health tracking reimagined Know your body, trust yourself. 15% off with code LWBW15 at nowatch.com *** The Great British Veg Out How to support your gut, energy, and hormones by eating more — not less. 👉 sarahannmacklin.com/vegout Reset Your Health If your body feels off after stress, travel, or burnout — this is where to start. 👉 sarahannmacklin.com/reset-your-health *** Let’s be friends! 📷 Instagram: / sarahannmacklin 📹 Subscribe: / @livewellbewellsarah 🐦 Twitter: / sarahannmacklin 📱 TikTok: / livewellbewellpodcast 💌 Newsletter: https://sarahmacklin.substack.com/

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