Why Different Neuron Parts Learn Differently?

Artem Kirsanov June 6, 2025
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Artem Kirsanov

@artemkirsanov

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Exploring how neural systems learn and compute — at the intersection of neuroscience, computer science, and mathematics. Created by a Harvard neuroscience researcher.

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To try everything Brilliant has to offer—free—for a full 30 days, visit https://brilliant.org/ArtemKirsanov . You’ll also get 20% off an annual premium subscription Socials: X/Twitter: https://x.com/ArtemKRSV Patreon: https://patreon.com/artemkirsanov My name is Artem, I'm a graduate student at NYU Center for Neural Science and researcher at Flatiron Institute. In this video we explore a recent study published in Science, which revealed that different compartments of pyramidal neurons (apical vs basal dendrites) use different plasticity rules for learning. Link to the paper: https://www.science.org/doi/10.1126/science.ads4706 Outline: 00:00 Introduction 01:23 Synaptic transmission 06:09 Molecular machinery of LTP 08:40 Hebbian plasticity 11:21 Non-Hebbian plasticity 12:51 Hypothesis 14:42 Experimental methods 17:10 Result: compartmentalized plasticity 19:30 Interpretation 22:01 Brilliant 23:08 Outro Music by Artlist This video was sponsored by Brilliant

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