Why Do Redheads Need MORE ANESTHESIA Than Everyone Else?

Danesthesia September 10, 2025
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Danesthesia is your inside look at anesthesia, surgery, and the science of the human body. Hosted by anesthesiologist Dr. Daniel Medel, this channel breaks down what really happens in the operating room, explains medical mysteries, and shares unbelievable anesthesia stories. Learn about anesthetic drugs, surgery safety, and what patients experience before, during, and after anesthesia, in an engaging, easy-to-understand way. Subscribe for fascinating medical stories, anesthesia explained, and behind-the-scenes surgery insights.

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Did you know that natural redheads often need more anesthesia than brunettes or blondes? 🤯 This isn’t a myth—it’s backed by science, genetics, and years of clinical experience in anesthesiology. In this video, we’ll dive into: 🔬 The role of the MC1R gene in red hair and pain perception 💉 Why studies show redheads require up to 20% more anesthesia 😲 How pain sensitivity differs in redheads vs. others 🏥 What anesthesiologists and dentists should know when treating redhead patients 🧬 Why this is a perfect example of personalized medicine in action If you’re a redhead who’s ever said, “The numbing never works on me!” this video will explain why. And if you’re a healthcare provider, it’s a fascinating reminder of how genetics can shape our practice. 👉 Don’t forget to LIKE 👍, SUBSCRIBE 🔔, and COMMENT below: • Redheads: Have you noticed anesthesia works differently for you? • Providers: Have you seen this in your patients? ⸻ 👉 Next watch this video: https://youtu.be/-V3Kn7RclP0 📲 Follow me on social media: Instagram – https://www.instagram.com/DanesthesiaM TikTok – https://www.tiktok.com/@DanesthesiaM ⸻ 📚 References & Further Reading 1. Liem EB et al. Anesthetic requirement is increased in redheads. Anesthesiology. 2004;101(2):279-83. https://journals.lww.com/anesthesiology/fulltext/2004/08000/anesthetic_requirement_is_increased_in_redheads.5.aspx 2. Liem EB et al. Increased sensitivity to thermal pain and reduced subcutaneous lidocaine efficacy in redheads. Anesthesiology. 2005;102(3):509-14. https://journals.lww.com/anesthesiology/fulltext/2005/03000/increased_sensitivity_to_thermal_pain_and_reduced.5.aspx 3. Mogil JS. Pain genetics: past, present and future. Trends Genet. 2012;28(6):258-266. https://www.sciencedirect.com/science/article/pii/S0168952512000285 4. MedlinePlus Genetics: MC1R gene. https://medlineplus.gov/genetics/gene/mc1r/ 5. Bennett DLH, Woods CG. Painful and painless channelopathies. Lancet Neurol. 2014 Jun;13(6):587-99. https://www.sciencedirect.com/science/article/pii/S1474442214700249 ⸻ ⚠️ Disclaimer: The information provided in this video is for entertainment and general informational purposes only and should not be considered medical advice, diagnosis, or treatment. Watching this video does not create a doctor–patient relationship. Always seek the advice of a qualified healthcare provider with any questions you may have about a medical condition, procedure, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen or heard in this video. Stories shared in my videos are not necessarily events that happened to me personally. Certain stories may be adapted, fictionalized, or dramatized for the purpose of storytelling, entertainment, or to heighten suspense. In addition, names, locations, and other identifying details may have been altered or withheld to protect patient confidentiality and to ensure that no specific individual or event can be identified. Reliance on any information provided in this content is solely at your own risk. I make no representations, warranties, or guarantees about the accuracy, completeness, or applicability of the information presented, and I disclaim all liability for any loss, injury, or damage resulting from the use or misuse of this content. ⸻ 🔍 Keywords: Redheads, redheads anesthesia, why do redheads need more anesthesia, anesthesia explained, anesthesiology for beginners, anesthesia and genetics, redhead pain tolerance, anesthesia resistance in redheads, anesthesia science explained, personalized medicine anesthesia, why anesthesia works differently 📌 Hashtags: #Anesthesiology #Redheads #MedicalMystery #Genetics #Anesthesia #MedicalExplained #Surgery #Pharmacology #CriticalCare #ICU #Danesthesia

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