E209|挑战Neuralink,硅谷大佬争相涌入的超声脑机接口是什么?

硅谷101播客 October 13, 2025
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在人工智能领域打正火热的时候,OpenAI创始人Sam Altman正在低调布局一家脑机接口公司Merge Labs,用基因改造与超声波的方式在脑机接口领域正式跟马斯克竞争。 就在2025年上半年,越来越多关于超声脑机接口公司陆续得到硅谷顶级富豪的资本支持。这条路径与Neuralink这种需要破脑膜的方式完全不同,Neuralink是通过电信号进行通信的脑植入物,而另一个路径则是超声波检测到的血流信号来揭开大脑的秘密。 最有意思的是,我们从一个完全不同的技术路径再去看Neuralink,就像站在月球看地球,又打开了一个新世界,聊到最后我们会发现脑机接口、人工智能、机器人,正在朝着融合的方向发展,这就是硅谷有意思的地方。 【主播】 泓君,硅谷101创始人,播客主理人 【嘉宾】 彭雷,格式塔Gestala创始人兼CEO,脑虎,客如云创始人,复旦类脑院博士,天府锦城实验室研究员 【AIAS研讨会】 2025年10月27日-28日,陈天桥雒芊芊研究院和加州大学伯克利分校联合举办的AIAS 2025研讨会将于旧金山One Sansome举行,聚焦AI如何加速科学发展。本次活动大咖云集,光诺贝尔奖得主就有三位——Omar Yaghi、David Baker 和 Jennifer Doudna。活动可以免费参加,但席位有限,感兴趣的听众欢迎通过aias2025.org来报名。 https://aias2025.org/ 【你将听到】 01:00 AIAS 2025研讨会 整体地去解读大脑 03:56 传统电学脑机接口原理——通过电信号解码&编码大脑 05:12 为什么做超声脑机接口:整体地解读大脑,去接近思维意识的终极答案 08:47 功能核磁成像(fMRI)是人类第一次对大脑整体进行解码,但缺乏时序性 11:16 当脑机接口的时间和空间的分辨率都达到极致,大脑在我们面前就是透明的 12:34 目前最先进的Neuralink,只能覆盖大脑表面空间1.3‰ 14:43 以“摩尔定律”预测电学脑机接口发展,不断缩小的中美差距 电学vs超声,脑机接口优势比拼 17:41 空间覆盖上,一个超声脑机接口可覆盖大脑区域的25% 18:49 时效性上,都是实时,但电信号和血流信号天然存在时间差 20:43 电学脑机接口擅长“读”,做运动解码和语言解码 21:13 超声脑机接口擅长“写”,以相控阵方式对神经元产生影响 22:06 超声脑机接口的第一个应用场景:疼痛管理 24:17 超声脑机接口不存在“侵入式”,更易被接受 超声脑机接口的商业化前景 26:13 用于调控的超声能量大,用于大脑更需谨慎,拿证需时间 30:22 第二个场景:减少缺血性脑中风患者的神经元死亡 30:54 第三个场景:为阿尔茨海默提供治疗新路径 - 加速大脑内有害蛋白(Tau蛋白、Aβ蛋白)的代谢 - 打开血脑屏障,帮助AD药物进入大脑 - 直接作用于海马体,加强神经元再生能力 33:19 第四个场景:睡眠管理 34:30 更多场景:抑郁症等精神类疾病、成瘾、癫痫等 硅谷大佬隐秘布局超声脑机接口 37:22 盘点值得关注的5家超声脑机接口公司,都是谁在投? - Spire,陈天桥投资(该领域的主要股东) - Nudge,创始人Fred是Coinbase的co-founder,由Thrive Capital投资(特朗普亲家) - Forest Neurotech,主要捐赠者是Eric Schmidt(前Google CEO) - Sanmai,Reid Hoffman投资(LinkedIn创始人) - Merge Labs,Sam Altman成立(由OpenAI联合创始人) 41:28 AI大佬押注脑机接口,神经科学跟人工智能是一个硬币的两面 42:31 黑客帝国红蓝药丸现实版:是否要选择基因改造大脑? 44:12 人脑+AI融合共生的终极形态:人脑改造和数字颅骨 顶尖AI科学家们,如何从生命科学角度看AI 48:03 下一代AI可能告别冯诺依曼架构,变得更像大脑“湿件” 51:19 为什么拿了诺奖的“人工智能之父”Geoffrey Hinton说他想回到神经科学领域? 52:00 另一个诺奖得主、谷歌高管Demis,研究细胞AI化,还成立了Isomorphic Labs(同构实验室),要“治愈一切疾病” 进化了数百万年的人脑,还可以给AI带来哪些启示? 54:57 不同于语言模型的精确性,AI的下一代世界模型的模态是不可精确描述的 57:04 人工智能、具身智能、脑机接口——这三个事迟早会交叉在一起 58:40 如果我们无法破解大脑的工作机制,所有调控都是“瞎子摸象” 01:04:08 脑机接口能真正推动全脑视角的研究,成为生命科学底层的重要工具,如同基因测序 再聊聊创业 01:06:14 医疗领域的中美创业环境对比 01:11:29 马斯克说的“2028年实现知识和记忆上传”靠谱吗? 01:16:38 从嘉宾六次创业经历,看中国互联网20年创业浪潮 【相关阅读】 Sam Altman押注超声脑机接口新路径:基因疗法 + 超声成未来可能方案 https://mp.weixin.qq.com/s/VccgigE7aK_8GAjB-mH6qQ Spire:https://spire.us/ Nudge:https://nudge.com/blog/about-studies/ Forest Neurotech:https://forestneurotech.org/about-forest Sanmai:https://sanmai.tech/technology Merge Labs:https://mergelab.io/ 【监制】 泓君 【后期】 AMEI 【运营】 朱婕 【BGM】 In All Seriousness - Howard Harper-Barnes The Big Truth - August Wilhelmsson 【在这里找到我们】 公众号:硅谷101 收听渠道:Apple Podcast|Spotify|小宇宙|喜马拉雅|蜻蜓FM|荔枝FM|网易云音乐|QQ音乐 其他平台:YouTube|Bilibili 搜索「硅谷101播客」 联系我们:[email protected]

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