Protein in Your Urine? What It Really Means for Your Kidneys | Nephrologist Explains

Sean Hashmi, MD April 18, 2025
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Sean Hashmi, MD

@seanhashmimd

About

Your kidneys control more than you think—metabolism, aging, weight, and blood pressure. I teach you how to protect them before it's too late. I'm Dr. Sean Hashmi, a board-certified Nephrologist and Obesity Medicine Specialist. After 15 years of treating kidney disease and metabolic conditions, I realized something was broken. We wait until people are sick, then scramble to fix the damage. Losing my sister and watching my family's health struggles changed my path. I left the "treat the symptom" model to focus on prevention—teaching people the science of staying healthy. The SELF Principle Sleep. Exercise. Love. Food. Four pillars that protect your kidneys, reverse insulin resistance, and add years to your life. This framework guides everything I teach. New videos weekly on kidney health, metabolic health, longevity, and disease prevention. Practice kindness and gratitude—starting with your health.

Video Description

In this evidence-based guide, Dr. Sean Hashmi reveals the science-backed truth about proteinuria and shares practical, actionable strategies to protect your kidney health. Learn why this critical marker matters for your overall health and how early detection can prevent serious kidney damage. ABOUT THIS VIDEO Discover what protein in your urine actually signals about your kidney function, the different types of proteinuria, and how it's detected. Dr. Hashmi explains the latest research on how proteinuria affects your long-term health and provides specific evidence-based strategies for managing this condition at different stages. QUICK NAVIGATION 00:00 - Introduction 01:22 - What Is Proteinuria? 01:45 - Types of Proteinuria 02:31 - Measuring Proteinuria 03:59 - Why Does Proteinuria Happen? 04:54 - Causes: Tubular Proteinuria 05:34 - Causes: Overflow Proteinuria 06:31 - Why Proteinuria Matters 07:41 - The Protein Damage Cycle 08:54 - Signs and Symptoms 10:33 - Evaluation of Proteinuria 13:12 - Treatment and Management 14:56 - Lifestyle Modifications 17:40 - Key Takeaways and Conclusion KEY INSIGHTS Proteinuria is not just a symptom but actively contributes to kidney damage, creating a cycle that can accelerate kidney disease progression Even microalbuminuria (small amounts of protein) significantly increases cardiovascular risk and mortality Sodium restriction can reduce proteinuria by approximately 30%, making diet a powerful intervention ACE inhibitors and ARBs remain cornerstone therapies for persistent proteinuria, while SGLT2 inhibitors show promising benefits for diabetic kidney disease SCIENTIFIC REFERENCES KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease. Kidney International. 2024;105(4S). Carrero JJ, et al. Albuminuria Changes Are Associated With Subsequent Risk of End-Stage Renal Disease And mortality. Kidney International. 2017;91(1):244-251. Benzing T, Salant D. Insights into Glomerular Filtration and Albuminuria. The New England Journal of Medicine. 2021;384(15):1437-1446. Claudel SE, Verma A. Albuminuria in Cardiovascular, Kidney, and Metabolic Disorders: A State-of-the-Art Review. Circulation. 2025;151(10):716-732. ABOUT DR. SEAN HASHMI Dr. Sean Hashmi is a board-certified nephrologist specializing in kidney health, lifestyle medicine, and obesity medicine. He translates complex medical research into actionable strategies to help you maintain healthy kidneys and improve your overall wellbeing. CONNECT & GROW SUBSCRIBE for weekly evidence-based health content: https://www.youtube.com/channel/UC9LQOhavwlGM58bIWbnXTDA?sub_confirmation=1 Get free resources: https://selfprinciple.org Follow Dr. Sean: @seanhashmimd JOIN our community: [Click "JOIN" above for exclusive content] MEDICAL DISCLAIMER This content is for informational purposes only and does not constitute medical advice or create a doctor/patient relationship. Viewers use this information at their own risk. The content should not substitute for professional medical advice—always consult your physician for medical conditions. Never delay seeking medical care based on information from this video. Views expressed are Dr. Sean Hashmi's own and do not necessarily represent those of affiliated institutions. #KidneyHealth #Proteinuria #KidneyDisease #ChronicKidneyDisease #NephrologistExplains

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