Redesigning The Molecules of Life | Brian Greene & David Baker
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Nobel laureate David Baker joins Brian Greene to discuss groundbreaking work that leverages the chemistry of life to design powerful new molecules with wide ranging applications. This program is part of the Rethinking Reality series, supported by the John Templeton Foundation. Guest: David Baker Moderator: Brian Greene 00:00:07 - Introduction: David Baker and Protein Design 00:01:28 - How David Baker Shifted from Philosophy to Biology 00:04:58 - What Are Proteins and How Do They Function? 00:08:26 - How Many Proteins Exist and Have Been Studied? 00:11:33 - Why Protein Folding Is Crucial to Function 00:13:10 - How Scientists Predict Protein Structure 00:18:36- DeepMind's AlphaFold Breakthrough 00:25:25 - From Prediction to Design: Custom Proteins 00:27:53 - Making Proteins in the Lab: The Process 00:31:06 - Real-World Uses: Influenza & Snake Venom Blockers 00:33:04 - Generative AI for Protein Design 00:35:47 - Building Catalysts to Break Down Plastics & Methane 00:40:42 - Applications in Pharma and Disease 00:45:47 - Making Plants More Climate Resilient 00:51:38 - Future of Protein-Based Machines 00:54:20 - Neurodegenerative Disease Research 00:59:23 - Brain-Computer Interfaces and Sensors 01:01:48 - Adapting to Deep Learning: A Scientist’s Mindset 01:06:17 - Where AI and Physics Methods Intersect VISIT our Website: http://www.worldsciencefestival.com FOLLOW us on Social Media: Facebook: / worldsciencefestival Twitter: / worldscifest Instagram: / worldscifest TikTok: / worldscifest LinkedIn: / world-science-festival #worldsciencefestival #briangreene #biology
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